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Understand the story behind your symptoms.

Get solutions for optimal midlife health.

The Smarter Way

Personalized Functional Medicine

• Resilient Brain Program

• Intelligent Menopause Program

• Concierge Wellness Program

Dr Manna Semby ND

The Only Menopause Society & ReCODE 2.0 Certified Functional Medicine Doctor in San Diego

You Belong Here If You:

  • Are worried about your brain health. Turn brain fog, memory lapses, and cognitive concerns into mental clarity and confidence with science that address the root causes of cognitive decline.
  • Want to reclaim yourself during midlife chaos. Navigate perimenopause and menopause with precision, not guesswork — restoring the sleep, energy, mood, and vitality you thought were gone forever.
  • Want a true partner in your health journey. Proactive, personalized medicine with a doctor who knows your history, coordinates your care, and catches problems before they become crises.

Areas of Focus

brain

Brain Health

Women are disproportionately affected with dementia, with changes beginning 20 years before diagnosis.

Early evaluation of risk, early detection and intervention are everything.

Based on Dr. Bredesen’s ReCODE 2.0 protocol

Menopause

Menopause is an inflection point that determines the trajectory of your mental, emotional and physical health.

Optimizing your whole health at this stage creates the right foundations for vibrant whole body health for the second half of your life so you can pursue your goals and dreams.

flame metabolism

Concierge Wellness

For unhurried, comprehensive care appointments that last as long as they need to.

Time to discuss the full picture of your health, your goals, your concerns.

Medicine that treats you as a whole person, not a series of isolated symptoms.

Watch my conversation with Dr. Bredesen as we explore his evidence-based ReCODE 2.0 protocol that prevents and reverses dementia in most cases.

Stop Dementia Before It Starts

This pioneering approach—backbone of Aruna’s Brain Health program—has already transformed the brains of many women.

ARUNA and ReCODE Interview
TEDx San Diego Dr Manna Semby speaking

Breaking the Silence on Perimenopause

It is time for you to have precision medicine that treats your perimenopause and menopause symptoms as seriously as any other health condition—targeting your hormones, brain, and metabolism to restore your power and bandwidth.

Book Your Initial Strategy Call

If you want more than surface-level solutions, talk to me about medical care that works for you.

The Aruna Method™ Approach

Assess

  • Comprehensive blood biomarkers – cardiometabolic, hormonal, nutrition etc.
  • Advanced functional testing – gut, toxins, genomics, inflammation etc.
  • Intakes, assessments and cognitive performance evaluation
  • Real-time metabolic monitoring

Rebuild

  • Personalized protocol creation based on your unique test results and genetics
  • Precision supplementation
  • Monthly strategy consultations
  • Concierge level support for regular guidance
  • Health coaching, if chosen
  • Oral & sleep screening, if chosen

Optimize

  • Measurable outcome tracking – biomarker trends, cognitive performance, energy, sleep
  • Protocol refinement
  • Follow-up retesting
  • Systemic, data-driven transformation to create measurable, sustainable improvements.

Dr. Manna: Committed to Your Care

My philosophy is built on one fundamental belief: midlife women deserve healthcare that honors both their intelligence and their humanity.

I believe that you are not a collection of symptoms. You want a doctor who will not only endeavor to understand your story well but also bring science, compassion and true partnership to the relationship. I want the same for you.

Dr Manna Semby ND

Testimonials

What Our Patients Say

5 stars

“In my early 30s, I would never have imagined that my PCOS and PMDD had anything to do with hormones. Thanks to Dr. Manna, I got educated on testosterone, insulin resistance and female hormones. When my hormone levels got fixed, a lot of my issues were resolved.”

Lucy C.
5 stars

“I have always been healthy. I ate well, worked out all the time and took really good quality supplements. But in my 40s I started to struggle with fatigue and insomnia in the 2nd half of my periods. When Dr. Manna tested my hormone levels, I realized that I needed to supplement just a bit to get my sleep and energy back. Now I feel great through the whole cycle! I also know to come back and see her when things begin to get messed up again as I get deeper into perimenopause.”

Sunita M.
5 stars

“I had gone through menopause just recently but had been too busy to start BHRT. I felt brain fog and exhaustion at an unimaginable level in addition to night sweats and hot flashes. What was I thinking? Or not thinking?? After starting bio-identical hormones in a very thorough and deliberate manner with Dr. Manna, I literally felt my brain come alive again. My energy came back, night sweats and hot flashes disappeared and I feel like my old self again!”

Linda S.
5 stars

“When Dr. Manna told me that most of my problems were due to mold toxicity, I found it hard to believe. I kept pushing back…but I was not getting better. After many weeks I agreed to do the mold test. It was all very high mold. I finally started to listen to her. My symptoms of shaking, vibrating, anxiety, ringing in my ears began to get better. I did another mold test a few weeks ago and it shows mold is coming down. My symptoms are better. I am happy I listened to her.”

Ming J.
5 stars

“My gut had a lot of issues for many years. I travel a lot and eat all kinds of food. I also had brain fog and anxiety. I was having a lot of relationship issues. When I talked to Dr. Manna, it was like talking to a friend. She encouraged me to do the healing work on myself and helped me with my gut and detox.”

Steve M.
5 stars

“I have an extensive family history of dementia. I am terrified I will also get it. I am working with Dr. Manna to keep it at bay. She follows Dr. Bredesen’s protocol to check all my body systems and points out what needs work and helps me do it. I’m so glad I found her.”

Jade C.

Exclusive Aruna Method™ Programs

1
Total Rebuild

Resilient Brain

9-Month Brain Optimization Program

Prevent and Reverse Early Cognitive Decline

  • Flagship, most comprehensive program.
  • Encompasses the Intelligent Menopause program.
  • For women with family history of personal genetics of dementia.
  • Based on Dr. Bredesen’s ReCODE 2.0 protocol
2
Hormone Mastery

Intelligent Menopause

6-Month Hormone Mastery Program

Navigate Perimenopause and Menopause with Confidence

  • Comprehensive program to navigate the menopausal transition.
  • Optimize cardiometabolic, hormonal, immune, bone, sexual and overall health.
  • Bioidentical hormone optimization tailored to your physiology.
3
Concierge Continuity

Concierge Wellness

Ongoing Longevity & Wellness Program

Trusted Partnership To Help Address Health Concerns Continuosly

  • Proactive, preventive medicine to keep you healthy.
  • Quick and easy access to Dr. Manna, as needed.
  • Address health concerns as they come up instead of researching problems & solutions on your own.

Ready to Feel Like Yourself Again?

Your brain fog doesn’t have to be permanent. Your hormones can work for you, not against you. Your future can be brighter than your present.

Frequently Asked Questions

What makes The Aruna Method™ different from other wellness programs?

The Aruna Method™ is uniquely tailored to address the specific health challenges of midlife women, using a personalized and integrative approach that combines conventional and functional medicine.

How long does it take to see results?

While individual results may vary, many clients begin to notice improvements within the first few weeks. Our programs are designed to provide long-lasting benefits over a structured period.

What types of lab tests are included in the programs?

Our programs include comprehensive blood labs, toxin screenings, digestive health tests, food sensitivity testing, and more, depending on the chosen program.

Can I participate in the program if I live outside of the local area?

Yes, our programs are designed to accommodate clients both locally and remotely through virtual consultations and telemedicine.

From the Blog

The Biology of the “Broken Rung”

Dr Manna Semby Avatar
December 18, 2025
Read More
Flat lay of various educational plastic anatomy models including organs and bones for study.

The Bone-Brain Axis: What Your Bone Health Says About Your Brain

Dr Manna Semby Avatar
December 7, 2025
Read More

Perimenopause Is the Fall That Ends With the Final Menstrual Period.

Dr Manna Semby Avatar
December 1, 2025
Read More

Serving Our Community

San Diego’s Premier Brain, Hormone & Metabolic Wellness

Carlsbad Location Serving La Jolla, Del Mar, Encinitas, Solana Beach, Rancho Santa Fe, and all of San Diego County

California’s only ReCODE-certified functional medicine practice specializing in women’s cognitive health

Virtual consultations available throughout California

Address

5938 Priestly Drive, Suite 103
Carlsbad CA 92008

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