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Midlife Transformation

Precision medicine:
Feel like yourself again.

Signature Wellness Programs for the discerning woman.

Dr Manna Semby ND

When you understand that true health transformation requires depth, partnership, and time, you are ready for Aruna. If you value an authentic relationship with your doctor who sees you as a whole person, not just a collection of symptoms, I invite you to apply.

The Program Advantage:

Depth: Single consultations, no matter how thorough, are like reading one chapter of your health story. They capture a snapshot but miss the nuanced patterns and evolving dynamics that become visible only through sustained observation—insights essential for profound, lasting transformation.

Partnership: Aruna’s comprehensive programs create a therapeutic partnership that evolves with you. Through months of dedicated collaboration, we uncover root causes, track biomarker improvements, adjust protocols based on your unique responses, and celebrate meaningful progress together.

Superior Outcomes Through Sustained Support

Consistency: Research consistently shows that lasting health transformations require consistent guidance over time. Our program participants experience:

  • Deeper Understanding: We identify complex patterns that single visits simply cannot reveal
  • Personalized Evolution: Your protocol adapts as your body responds and your needs shift
  • Sustained Motivation: Regular touchpoints and education keep you engaged and empowered
  • Measurable Progress: Serial testing reveals objective improvements that validate your investment
  • Lasting Change: Skills and habits developed over months become lifetime foundations
  • Comprehensive Care: We address interconnected systems rather than isolated symptoms

The women who choose our programs don’t just feel better temporarily—they experience fundamental shifts that enhance their vitality for decades to come.

Exclusive Aruna Method™ Programs

1
Total Rebuild

Resilient Brain Program

9-Month Brain Optimization Program

Prevent and Reverse Early Cognitive Decline

  • Flagship, most comprehensive program.
  • Includes the Intelligent Menopause program.
  • For women with family history or personal genetics of dementia.
  • Based on Dr. Bredesen’s ReCODE 2.0 protocol.
2
Hormone Mastery

Intelligent Menopause

6-Month Hormone Mastery Program

Navigate Perimenopause and Menopause with Confidence

  • Comprehensive program to navigate the menopausal transition.
  • Optimize heart, metabolic, hormonal, immune, bone, sexual and overall health.
  • Bioidentical hormone optimization tailored to your physiology.
3
Concierge Continuity

Concierge Wellness

Ongoing Longevity & Wellness Program

Trusted Partnership to Help Address Health Concerns Continuously

  • Proactive, preventive medicine to keep you healthy.
  • Quick and easy access to Dr. Manna, as needed.
  • Address health concerns as they come up instead of researching problems & solutions on your own.
5 stars

I’m beating Alzheimer’s thanks to Dr. Manna Semby! She gets 5 stars for her knowledge, organization, communication, working with me to solve problems, hand holding and overall an outstanding caregiver! I’m her very thankful patient and I happen to be a nurse for 50 years….I know a thing or two…

Mary Barth

Registered Nurse

Program Details

1

Total ReBuild

Resilient Brain

9-Month Brain Optimization Program

Prevent and Reverse Early Cognitive Decline

Dementia doesn’t happen overnight—it develops over decades. Yet our medical system waits until the damage is done, then offers treatments that fail to restore what’s been lost. This reactive approach has left families watching helplessly as their loved ones decline.

Dr. Dale Bredesen’s ReCODE 2.0 Protocol transforms cognitive care through personalized, evidence-based intervention. Instead of a one-size-fits-all approach, comprehensive testing reveals your individual risk factors, enabling us to create a targeted strategy that has proven successful in preventing and reversing early dementia.

Our Brain Clarity and Resilience Program harnesses the power of the ReCODE 2.0 Protocol for women who do not accept ‘brain fog’ as normal. From addressing current memory concerns to proactively protecting your cognitive future, this program provides unparalleled neurological assessment and optimization.

What’s Included

  • The Latest Blood Based Biomarkers for Brain Health:
    • Evidence of amyloid, immune cell activation and inflammation in the brain.
    • Very useful markers to show if you are “at-risk” for dementia.
  • Annual Membership to the Apollo Health Portal includes:
    • A detailed report based on your initial blood labs, delineating different risk factors for your brain health.
    • The risk factors which are the doorway to further detailed functional medicine testing as well as basis of a Personalized Plan for you.
    • Access to have your case discussed case directly with Dr. Bredesen.
    • Access to support groups on topics such as mold detox and overall protocol support.
  • Blood Labs Through Quest:
    • Comprehensive markers such as cardiometabolic health, hormones, inflammation, nutrition, liver/kidney health and others.
  • Subjective Cognitive Assessments:
    • Interview and intake based
  • Online Cognitive Assessments:
    • Non-invasive neurocognitive testing
    • Cognition stress tests for
      • Neurocognition index
      • Memory
      • Psychomotor speed
      • Complex attention
      • Cognitive flexibility
  • Functional Medicine Labs:
    • Food sensitivities (blood)
    • Pathogen associated immune reactivity (blood)
    • Gut health (stool)
    • Nutritional evaluation (blood, urine)
    • Environmental & biotoxins (urine)
    • Genomic testing (saliva)
  • Continuous Glucose Monitoring:
    • To understand your body’s response to food and stress.
    • Critical in deciding the right therapeutic actions to optimize your metabolic health.
  • Strategy Consultations:
    • Monthly one on one in-depth sessions with Dr. Manna.
    • Create your Plan based on your health goals, results of tests and evaluations and agreed upon outcomes.
    • Review progress regularly, refine Plan based on your progress and feedback, optimize metrics of health to achieve the desired outcomes.
  • Concierge Support:
    • Direct access between appointments for questions and guidance.
  • Educational Video Library:
    • Ongoing learning modules about brain health and optimization.
  • Supplements (add on):
    • 15% discount on professional grade supplements based on testing and desired outcomes.
  • Professional Health Coaching (add on):
    • Dedicated support to implement lifestyle changes.
  • Oral Health & Sleep Screening (add on):
    • Assessment of crucial factors affecting cognitive function.
  • Follow-up Retesting (add on):
    • Monitoring progress with repeat biomarkers and cognitive assessments.

Program Focus

  • Assess brain health with the latest tools
  • Advanced whole-body assessment for inflammation and other red flags
  • Prevention of dementia and reversal of subjective and early mild cognitive decline
  • Symptom management and elimination
  • Assess body burden of toxins and safe detox
  • Bone health optimization
  • Cardiovascular protection
  • Sleep and mood stabilization
  • Energy and libido restoration
  • Long-term health planning

Investment Period

9 months of dedicated partnership

2

Hormone Mastery

Intelligent Menopause

6-Month Hormone Program

Navigating perimenopause and menopause intelligently requires more than an HRT prescription. True optimization means understanding how hormonal changes ripple through every system in your body—then strategically supporting your heart, metabolism, digestion, immunity, sexuality, and mental-emotional wellbeing.

Aruna’s intensive Intelligent Menopause program offers a deep dive into hormonal optimization for women ready to move through their menopausal transition with grace, vitality, and minimal disruption to their lives.

Designed for women who want comprehensive support during this pivotal life stage, this program combines cutting-edge hormone balancing with lifestyle optimization to help you not just survive menopause but thrive through it.

What’s Included

  • Blood Labs Through Quest:
    • Comprehensive markers such as cardiometabolic health, hormones, inflammation, nutrition, liver/kidney health and others.
  • Functional Medicine Labs:
    • Pathogen associated immune reactivity (blood)
    • Gut health (stool)
    • Nutritional evaluation (blood, urine)
    • Environmental & biotoxins (urine)
    • Genomic testing (saliva)
  • Continuous Glucose Monitoring:
    • To understand your body’s response to food and stress.
    • Critical in deciding the right therapeutic actions to optimize your metabolic health.
  • Strategy Consultations:
    • Monthly one on one in-depth sessions with Dr. Manna.
    • Create your Plan based on your health goals, results of tests and evaluations and agreed upon outcomes.
    • Review progress regularly, refine the Plan based on your progress and feedback, optimize various metrics of health to achieve the desired outcomes.
  • Concierge Support:
    • Direct access between appointments for questions and guidance.
  • Educational Video Library:
    • Ongoing learning modules about brain health and optimization.
  • Supplements (add on):
    • 15% discount on professional grade supplements based on testing and desired outcomes.
  • Professional Health Coaching (add on):
    • Dedicated support to implement lifestyle changes.
  • Oral Health & Sleep Screening (add on):
    • Assessment of crucial factors affecting cognitive function.
  • Follow-up Retesting (add on):
    • Monitoring progress with repeat biomarkers and cognitive assessments.

Program Focus

  • Advanced hormonal assessment and balancing
  • Symptom management and elimination
  • Assess body burden of toxins and safe detox
  • Bone health optimization
  • Cardiovascular protection
  • Sleep and mood stabilization
  • Energy and libido restoration
  • Long-term health planning

Investment Period

6 months of focused hormonal transformation

3

Concierge Continuity

Concierge Wellness

Ongoing Longevity & Wellness Program

Optimize Your Body’s Core Systems

The Concierge Wellness Program is a high-touch personalized experience designed to optimize your hormones, brain health, metabolism, and cellular aging all year long. Using advanced diagnostics and personalized protocols, we address the root causes of fatigue, inflammation, weight changes, and cognitive decline before they become problems. This is sustainable, science-driven health for women who want to stay sharp, strong, and vibrant in every decade ahead.

What’s Included

  • Bi-annual Blood Labs Through Quest:
    • Comprehensive markers such as cardiometabolic health, hormones, inflammation, nutrition, liver/kidney health and others.
  • Functional Medicine Labs (as needed):
    • Genomics
    • Hormones
    • Gut health (stool)
    • Environmental & biotoxins (urine)
    • Food sensitivities
  • Continuous Glucose Monitoring:
    • To understand your body’s response to food and stress.
    • Critical in deciding the right therapeutic actions to optimize your metabolic health.
  • Strategy Consultations:
    • Quarterly one on one in-depth sessions with Dr. Manna.
    • Access to Dr. Manna for questions and urgent concerns.
    • Continuously updated Plan based on your health goals, results of tests and evaluations and agreed upon outcomes.
    • Review progress regularly, refine the Plan based on your progress and feedback, optimize metrics of health to achieve the desired outcomes.
  • Concierge Support:
    • Direct access between appointments for questions and guidance.
  • Educational Video Library:
    • Ongoing learning modules about brain health and optimization.
  • Supplements (add on):
    • 15% discount on professional grade supplements based on testing and desired outcomes.
  • Follow-up Retesting (add on):
    • Monitoring progress with repeat biomarkers and cognitive assessments.

Program Focus

  • Bi-annual in-depth labs and quarterly consultations
  • Protocol adjustments as needed
  • Priority scheduling for urgent concerns
  • Concierge support
  • 15% discount on high quality supplements

The promise: Focus on longevity and health span

Investment Period

Ongoing

Choosing Your Path

Resilient Brain Program

Start with this if:

  • You have personal genetics that increase your susceptibility to dementia
  • You have family history of dementia
  • You are concerned about brain symptoms
  • You want the most comprehensive transformation

Intelligent Menopause

Start with this if:

  • Your issues are primarily energy, weight, or hormonal
  • There are no cognitive concerns
  • A nine-month commitment feels too long

Concierge Wellness

Start with this if:

  • You don’t have immediate concerns related to brain or the menopausal transition
  • You want to optimize your overall health and wellbeing
  • You want to partner with a doctor who knows your medical history intimately
  • You prefer on ongoing relationship instead of a time bound program

Ready to Begin Your Transformation?

Commitment: These programs are designed for women who understand that exceptional health requires exceptional commitment—both from you and from your healthcare team. Each program represents a partnership in your wellness journey, providing the depth, continuity, and personalized attention that creates lasting change.

Progress: Your midlife years can be your most vibrant yet. Let’s make them extraordinary together.

Decide: Not sure which is right?

Watch the Video: Your NEW Chapter Begins Here and schedule your initial strategy call. We will discuss your personal medical history and health goals. We will evaluate if we are a good match to work together. I will advise which program is a good match for you. Even if we decide not to work together, you will walk away with valuable information that you can use to improve your health and wellness on your own or with another doctor.

Schedule Your Discovery Call

Comprehensive wellness programs for individualized healthcare

Combining precision and functional medicine with proven natural therapies

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