Free live online Masterclass
Protect your brain health.
Understand your risk — and what you can do.
Learn what to do now for the brain you want later.

Midlife Brain Health
Join Dr. Manna Semby for a live masterclass on brain health, the actions you can take to protect it, and why midlife is an important time to start paying attention.
Before we meet, you’ll complete the Brain Health Check-In. She’ll review your responses before the live masterclass so the conversation reflects your concerns.
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You don’t have to wait until something is wrong to start paying attention to your brain health.
Maybe you’re noticing changes in your memory or focus.
Maybe the brain fog that started with menopause is persisting despite you doing everything right.
You want to know:
What do I need to pay attention to now to protect my future brain health?
You want to understand your risk.
You want to know what risk factors you can change.
And you want to know what you can start doing now.
Women at Midlife Ask:
“What shapes my future brain health?”
Family history and genetics
If one or more of your family members had Alzheimer’s or mixed dementia, that is significant. But increased genetic risk is not the same as a diagnosis. We’ll talk about what family history and genetic information can tell you — and what they cannot.
Menopause and hormonal change
The brain plays a central role in menopause. We’ll look at why this period deserves a place in the brain-health conversation—and why the relationship between hormones, HRT and long-term cognitive health is more nuanced than many women have been led to believe.
Cardiovascular and metabolic health
Your brain depends on a healthy vascular system and a continuous supply of oxygen and nutrients. Blood pressure, lipids, glucose regulation and other aspects of cardiovascular and metabolic health matter to the health of your brain as well.
Sleep, stress and mood
Sleep, mood and stress are closely connected to how your brain functions and how you feel day to day. We’ll discuss fragmented sleep, conditions such as sleep apnea, anxiety and chronic stress — and why persistent changes in sleep, mood or cognitive function should not be dismissed as “just stress.”
Other modifiable factors
You know about exercise and nutrition. But what about the load of environmental toxins, chronic infections or gut health that silently impact your brain health? We will discuss all of the above.

“I meet many of these criteria. I have been considering taking steps — but unsure where to start. Gyn, functional med, menopausal specialist, genetic testing for risk (father passed from Alzheimer’s @ 80). This gives me the info I need.”
— Past Masterclass attendee.
But knowing the list isn’t enough.
Today we have more ways than ever to understand brain-health risk and detect signs of disease earlier.
But information alone doesn’t tell you what to do next.
There is no single brain-health plan that makes sense for every woman.
The important question is: what does your particular risk look like, and what deserves your attention now?
The Real Question:
Which factors matter to you?
Two women can have the same concern about Alzheimer’s and very different risk profiles.
One may need to pay particular attention to cardiovascular and metabolic health. Another may have significant sleep problems. Another may be navigating menopause alongside a strong family history. For many women, several factors overlap.
The goal isn’t to do everything. It’s to understand your risk, identify what deserves attention, and know where to start.
That’s the approach I’ll introduce you to in the Brain Health Masterclass.
What You’ll Leave with:
A clearer way to think about your brain health.
And your next steps.
What brain-health risk actually means
And why family history matters without determining your future.
Which parts of brain-health risk are modifiable
And why different factors matter for different women.
Where menopause fits into brain health
And why this transition is an important time to think about your future brain health.
Why different women have very different risk landscapes
There is no single brain-health plan that applies to everyone.
What questions are worth asking next
So you can make more informed decisions about what deserves your attention next.
What steps you can take next
Understand the next steps you can take for your long-term brain health.
Annie’s Story

What Annie Was Experiencing
When Annie came to see me, she was 52 years old and deeply worried about what was happening to her brain. Her grandmother had died with dementia, and her mother was beginning to show signs of cognitive decline.
What We Discovered
Annie was struggling with severe brain fog, anxiety, poor sleep, and overwhelming fatigue.
Multiple factors were affecting how she felt and how her brain functioned, including mood changes, poor sleep, chronic stress, multiple medications, and other underlying health challenges that had never been addressed as part of a bigger picture.
What Changed for Annie
As we addressed the factors driving her symptoms, Annie’s symptoms began to change. Her sleep improved. Her anxiety settled. The mental fatigue and brain fog lifted. She began waking up with energy and feeling like “she was back” for the first time in years.
By the end of our work together, Annie had regained confidence in her brain, her health, and her future.
Menopause and Your Brain
Menopause hits your brain too
Most women think about menopause in terms of periods, hot flashes and hormones.
Menopause is a brain event.
As estrogen and progesterone fluctuate and eventually decline substantially, the brain adapts.
Many women experience changes in memory, focus, mood, sleep and cognitive stamina during this period.
We’ll talk about what’s happening, why menopause belongs in the brain-health conversation. We will also discuss the role of hormones in long-term cognitive health.

Whether you’re going through menopause now or are years beyond it, understanding where menopause fits into your larger brain-health picture still matters.
Complete the Brain Health Check-In:
Tell me what’s bringing you here.
Complete the Brain Health
Check-In
Dr. Manna reviews your responses
Your responses help drive the Masterclass
After you register, you’ll be invited to complete the Brain Health Check-In.
You’ll answer three short questions about what’s bringing you here and what you most want to understand.
The Brain Health Check-In and masterclass are educational and do not constitute an individualized medical evaluation or establish a doctor-patient relationship.
get clear on your next steps
Leave the class understanding:
Why I Care About This.
I work with midlife women on menopause, brain health and healthy aging because I believe women should have the ability to live their lives with independence and agency.
Menopause is a particularly important time to think about brain aging because the brain changes during this transition. This is also a time when women begin thinking differently about the decades ahead, and rightly so.
My work is about helping women understand their whole brain and body health, identify what deserves attention now, and make informed decisions about what they want to do next.
Dr. Manna Semby, ND, MSCP, IFMCP

Past Masterclass Participants Say:
Thank you for this session. I will be sharing this video with my two sisters with dementia and Alzheimer’s.
— Past Attendee
This seminar has been very helpful. My husband has been diagnosed with MCI. This helps me to decide if I need to do this for myself.
— Past Attendee
Thank you for this valuable session today. I applied already.
— Past Attendee
I hope you’ll join me live
Before we meet, I’ll review the Brain Health Check-In responses from the women who have registered.

Free live online Masterclass
Protect your brain health.
Understand your risk — and what you can do now.
Learn what to do now for the brain you want later.
Frequently Asked Questions
Is this only for women with a family history of dementia?
No.
Family history is one reason women begin thinking seriously about brain health, but it isn’t the only one.
This masterclass is for women who are concerned about their future brain health and want to learn what they can do today to protect it.
Do I need to be experiencing memory problems?
No.
In fact, this masterclass is particularly relevant if you want to think about brain health before significant cognitive problems develop.
If you are experiencing new, progressive or significant cognitive changes, those warrant appropriate clinical evaluation rather than relying on a masterclass such as this one.
What if I’m already taking hormone replacement therapy (HRT)?
That’s fine.
Hormones are a part of a much larger brain-health picture. We’ll discuss menopause and hormonal changes as well as HRT.
Is this medical care?
No.
This is an educational group masterclass. Dr. Manna cannot assess your individual health or make personalized medical recommendations during the session.
The Brain Health Assessment you complete before the masterclass is also educational and does not establish a doctor-patient relationship.
Will there be a replay?
Yes.
Registered participants will receive access to the replay.
I hope you’ll join live so you can participate in the full experience.
Register for the Masterclass
For your privacy
The Brain Health Check-In and masterclass are educational and do not constitute an individualized medical evaluation or establish a doctor-patient relationship.
