Personalized Medicine For Women 40-65
Intelligent Menopause
Six months of health partnership for your body and brain.
Truly Personalized Medicine
Maybe you’re trying to decide whether hormone therapy is right for you. Maybe you’re already taking hormones but still don’t feel as well as you expected.
Systems thinking for complex challenges
Perhaps sleep, energy, weight, mood, sexual health, strength, joint pain, cholesterol or blood sugar have changed—and you know it’s not just one thing.
Menopause is for life
Or perhaps you’re years past menopause and asking a different question now:
What does my body and brain need at this point in my life?
Intelligent Menopause is a six-month personalized medicine program designed to answer that question with you.
A personal health roadmap
Over eight physician visits, we establish your goals and baseline, investigate your health in depth, create and implement a prioritized treatment plan, measure your response and continually refine our approach based on what we learn.
A medical partnership
This isn’t a one-time menopause consultation or a prescription you take home and figure out on your own.
We have six months to do the work together.
Your Intelligent Menopause Roadmap
A journey that unfolds in partnership
Establish your goals and baseline
We begin with a comprehensive medical evaluation of your menopause journey, symptoms, personal and family history, medications, current or previous hormone therapy, lifestyle, previous testing and the concerns that brought you to me.
We define your goals and establish your starting point through clinical assessment and targeted laboratory investigation.
Build a 360° view of your health
Hormones matter, but they are not the only thing we investigate. Depending on your history and concerns, we may evaluate cardiovascular and metabolic health, thyroid function, nutritional status, bone and muscle health, sleep, inflammation, gut health, mental and cognitive health, sexual health and other factors relevant to you.
The purpose is to determine what matters in you.
Prioritize and create your treatment plan
I bring your history, symptoms, examination and laboratory findings together and determine what deserves attention first.
For one woman, that may be hormone therapy. For another, gut health may be the more important place to begin. For yet another, sleep, metabolic health, thyroid function, nutrient status or something else may be the more important place to begin.
We establish what we’re doing, why we’re doing it and what we will measure to know whether it is working.
Implement, measure and refine
Then we act.
Over the following months, we evaluate your response. Are you feeling better? How is your health changing? What does your health data tell us? Where can we improve?
We adjust treatment as needed and add the next priority when appropriate.
We don’t simply hand you a plan. We implement it together.
Measure your before and after
Toward the end of the program, we repeat selected laboratory tests and other measures and compare where you started with where you are now.
Your laboratory results are only part of the evidence. We also return to the goals you established at the beginning.
Did your sleep improve? Is your energy different? Are you stronger? Are you exercising again? Has your sexual health changed? Do you feel better? What improved objectively?
My job is to understand what all of that information means together.
Build your plan for what comes next
Layer in the next major intervention while continuing what is working.
bHRT
Yes, we can talk about hormone therapy.
You may be considering hormone therapy for the first time. You may already be taking it and wondering whether your current treatment is right for you. You may be years beyond your final period and wondering whether starting now is appropriate.
Or your medical history may make the conversation more complicated—because of breast cancer, cardiovascular disease or another chronic illness.
We consider hormone therapy in the context of your symptoms, goals, medical history, family history, current health and the available evidence.
The objective is not a predetermined yes or no.
Choices
Intelligent Menopause or Stay Sharp?
Intelligent Menopause
Intelligent Menopause is the six-month program for women whose primary questions center on menopause and midlife health.
Stay Sharp
Stay Sharp is the more extensive nine-month program for women whose brain health is the leading concern and warrants deeper investigation, including neurocognitive assessment, genomics and a broader brain-health evaluation.
More isn’t automatically better. The right program is the one whose depth and scope fit you.
Six months.
Eight physician visits. One personalized plan that evolves with you.
Intelligent Menopause includes:
Intelligent Menopause
Feel like yourself again.
This program is designed for women who want a deeper level of support to improve energy, focus, mood, sleep, hormonal health, and overall resilience during midlife.
Together, we develop and implement a personalized strategy designed around your unique biology, helping you restore confidence in your body, your brain, and your daily life.
Best for: Women seeking meaningful improvement in how they feel and function every day.
- Advanced Blood Labs:
- Comprehensive markers such as cardiometabolic health, hormones, inflammation, nutrition, liver/kidney health and others.
- Functional Medicine Labs:
- Environmental, mycotoxins & glyphosate (urine)
- Heavy metals (urine)
- Gut health (stool)
- Food sensitivities (blood)
- Nutritional evaluation (blood, urine)
- Pathogen associated immune reactivity (blood)
- Strategy Consultations:
- One on one in-depth sessions every four weeks with Dr. Manna.
- Create your Plan based on your health goals, results of tests and evaluations and agreed upon outcomes.
- Review progress regularly, refine the Plan based on your progress and feedback, optimize various metrics of health to achieve the desired outcomes.
- Concierge Support:
- Direct access between appointments for questions and guidance.
- Educational Video Library:
- Ongoing learning modules about brain health and optimization.
- Follow-up Retesting
- Monitoring progress with repeat biomarkers and cognitive assessments.
- Supplements (add on):
- 10% discount on professional grade supplements based on testing and desired outcomes.
- Continuous Glucose Monitoring: (add on):
- To understand your body’s response to food and stress.
- Professional Health Coaching (add on):
- Dedicated support to implement lifestyle changes.
- Oral Health & Sleep Screening (add on):
- Assessment of crucial factors affecting cognitive function.
- Advanced hormonal assessment and balancing
- Evaluate health of the body as a whole
- Assess body burden of toxins and safe detox
- Bone health optimization
- Cardiovascular protection
- Sleep and mood stabilization
- Energy and libido restoration
- Long-term health planning
- Your issues are primarily around midlife, menopause, energy, weight, or hormonal concerns
- Cognitive concerns are a concern, but not your primary focus
6 months of focused hormonal transformation $10,075
Flexible payment options are available.
Get The Early Advantage™
Intelligent Menopause
If menopause and midlife health are your highest priorities and you’re ready to work seriously and proactively on them, Intelligent Menopause is designed for you.

I’m beating Alzheimer’s thanks to Dr. Manna Semby! She gets 5 stars for her knowledge, organization, communication, working with me to solve problems, hand holding and overall an outstanding caregiver! I’m her very thankful patient and I happen to be a nurse for 50 years….I know a thing or two…
Mary Barth
Registered Nurse