TL;DR: Every night you sleep through a hot flash, your heart is on high alert, your blood pressure spikes, and blood flow to your brain is transiently reduced. Over…
I wrote this manifesto in the early drafts of my book. I didn’t plan it. It arrived fully formed, all at once, the way things arrive when you have…
TL;DR – Subjective symptoms cannot distinguish between reversible stress, hormonal disruption, or early neurobiological risk. Blood-based brain biomarkers can. Markers such as pTau-217, GFAP, and NfL reveal amyloid activity,…
TL; DR – If men lost testosterone the way women lose estrogen, it would be treated as a medical emergency, not a “life stage.” Men’s testosterone declines gradually and…
TL;DR: A new Alzheimer’s trial achieved what no previous trial has — every treated patient improved. The secret wasn’t a drug. It was addressing the full picture: metabolism, inflammation,…
TL;DR: The most consequential organs for you to understand in your body are your ovaries. They aren’t just egg storage and monthly cycles — they produce hormones that run…
A randomized controlled trial validates what I’ve seen in my practice: cognitive decline doesn’t have to be inevitable. TL; DR – A randomized controlled trial published December 30, 2025…
TL;DR: Your bones and brain decline together in midlife—not by coincidence, but because estrogen protected both and now it’s gone. A DEXA scan in your 40s isn’t just about…
What 300 million lab tests reveal about the menopause transition—and why we’ve been reading it backward TLDR: A study of 300+ million lab tests from 1.3 million women reveals…
Discover how Dr. Manna has been helping women understand their risk, identify the factors influencing their brain health, and take meaningful action to protect their future.
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